Fine Particulate Air Pollution and Adverse Birth Outcomes: Effect Modification by Regional Nonvolatile Oxidative Potential.

ABSTRACT:

Background

Prenatal exposure to fine particulate matter air pollution with aerodynamic diameter ≤2.5 μm (PM_2.5) has been associated with preterm delivery and low birth weight (LBW), but few studies have examined possible effect modification by oxidative potential.

Objectives

The aim of this study was to evaluate if regional differences in the oxidative potential of PM_2.5 modify the relationship between PM_2.5 and adverse birth outcomes.

Methods

A retrospective cohort study was conducted using 196,171 singleton births that occurred in 31 cities in the province of Ontario, Canada, from 2006 to 2012. Daily air pollution data were collected from ground monitors, and city-level PM_2.5 oxidative potential was measured. We used rando

SUBMITTER: Lavigne E 

PROVIDER: S-EPMC6108848 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature