Ontology highlight
ABSTRACT:
SUBMITTER: Sarmento MJ
PROVIDER: S-EPMC6109149 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Nature communications 20180824 1
Imaging of nuclear structures within intact eukaryotic nuclei is imperative to understand the effect of chromatin folding on genome function. Recent developments of super-resolution fluorescence microscopy techniques combine high specificity, sensitivity, and less-invasive sample preparation procedures with the sub-diffraction spatial resolution required to image chromatin at the nanoscale. Here, we present a method to enhance the spatial resolution of a stimulated-emission depletion (STED) micr ...[more]