Cumulative childhood adversity and adult cardiometabolic disease: A meta-analysis.

ABSTRACT:

Objective

Adverse childhood experiences may be associated with cardiometabolic morbidity and mortality in adulthood. There is heterogeneity in this literature regarding the type of items in cumulative adversity indices, sample sizes, demographics, and covariates. The present review used quantitative meta-analysis to examine this association and potential moderators.

Method

Included studies had a measure of cumulative adversity (an index of at least 2 adverse childhood experiences from age 0 to 18) and a measure of cardiometabolic disease: cardiovascular disease (CVD) clinical outcomes (hypertension, coronary heart disease, ischemic heart disease, myocardial infarction, stroke, cerebrovascular disease) and metabolic outcomes (diabetes, metabolic syndrome) at age 18 or older.

SUBMITTER: Jakubowski KP 

PROVIDER: S-EPMC6109976 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature