Impact of Very Early Physical Therapy During Septic Shock on Skeletal Muscle: A Randomized Controlled Trial.

ABSTRACT:

Objectives

As the catabolic state induced by septic shock together with the physical inactivity of patients lead to the rapid loss of muscle mass and impaired function, the purpose of this study was to test whether an early physical therapy during the onset of septic shock regulates catabolic signals and preserves skeletal muscle mass.

Design

Randomized controlled trial.

Setting

Tertiary mixed ICU.

Patients

Adult patients admitted for septic shock within the first 72 hours.

Interventions

Patients were assigned randomly into two groups. The control group benefited from manual mobilization once a day. The intervention group had twice daily sessions of both manual mobilization and 30-minute passive/active cycling therapy.

Measurements and main results

SUBMITTER: Hickmann CE 

PROVIDER: S-EPMC6110624 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature