Outcome Prediction of Acute Kidney Injury Biomarkers at Initiation of Dialysis in Critical Units.

ABSTRACT: : The ideal circumstances for whether and when to start RRT remain unclear. The outcome predictive ability of acute kidney injury (AKI) biomarkers measuring at dialysis initializing need more validation. This prospective, multi-center observational cohort study enrolled 257 patients with AKI undergoing renal replacement therapy (RRT) shortly after admission. At the start of RRT, blood and urine samples were collected for relevant biomarker measurement. RRT dependence and all-cause mortality were recorded up to 90 days after discharge. Areas under the receiver operator characteristic (AUROC) curves and a multivariate generalized additive model were applied to predict outcomes. One hundred and thirty-five (52.5%) patients died within 90 days of hospital discharge. Plasma c-terminal FG

SUBMITTER: Wu VC 

PROVIDER: S-EPMC6112021 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature