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Association between Helicobacter pylori infection and tumor markers: an observational retrospective study.


ABSTRACT: OBJECTIVE:Helicobacter pylori infection is a major cause of several cancers such as gastric, pancreatic and lung. The relationship between H. pylori and tumour markers continues to remain unclear. The primary goal of this study is to clarify the associations between H. pylori infection and six tumour markers (ie, carcinoembryonic antigen (CEA), cancer antigen (CA) 153, CA199, CA724, CA125 and alpha-fetoprotein (AFP)). The secondary goal is to provide understanding for further research about H. pylori infection and gastrointestinal cancer. DESIGN:Observational retrospective study. SETTING:The study was performed in Beijing, China, where enrolled subjects had all passed health examinations during the period of 2012-2016. Subjects were categorised into H. pylori (+) and H. pylori (-) group ac

SUBMITTER: Xu MY 

PROVIDER: S-EPMC6112394 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature