Risk profiles for acute health events after incident atrial fibrillation in patients with end-stage renal disease on hemodialysis.

ABSTRACT:

Background

Little is known about the cardiovascular risks of incident atrial fibrillation/flutter (AF) in patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD).

Methods

We studied older US patients who newly initiated HD for ESRD (2006-11) and who had not previously been diagnosed with AF, stroke, myocardial infarction (MI) or hip fracture. We used Cox regression with AF as a time-varying covariate, adjusted for socio-demographic characteristics and comorbidities to estimate hazard ratios [HRs (95% confidence intervals)] for the events of ischemic stroke, MI and death. Hip fracture served as a negative control outcome.

Results

We identified 85 377 older patients (mean age: 76.5 years) who initiated HD; of these, 14.3% were subsequently diagnosed wi

SUBMITTER: Airy M 

PROVIDER: S-EPMC6113645 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature