A functional micro-electrode mapping of ventral thalamus in essential tremor.

ABSTRACT: Deep brain stimulation enables the delivery of therapeutic interventions to otherwise inaccessible areas of the brain while, at the same time, offering the unique opportunity to record from these same regions in awake patients. The posterior ventrolateral thalamus has become a reliable deep brain stimulation target for medically-refractory patients suffering from essential tremor. However, the contribution of the thalamus in essential tremor, and even whether posterior ventrolateral thalamus is the optimal target, remains a matter of ongoing debate. There are several lines of evidence supporting clusters of activity within the posterior ventrolateral thalamus that are important for tremor emergence. In this study we sought to map the functional properties of these clusters through microele

SUBMITTER: Pedrosa DJ 

PROVIDER: S-EPMC6113647 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature