Genetic Factors Affecting Seasonality, Mood, and the Circadian Clock.

ABSTRACT: In healthy humans, seasonality has been documented in psychological variables, chronotype, sleep, feeding, metabolic and autonomic function, thermoregulation, neurotransmission, and hormonal response to stimulation, thus representing a relevant factor to account for, especially when considering the individual susceptibility to disease. Mood is largely recognized as one of the central aspects of human behavior influenced by seasonal variations. This historical notion, already mentioned in ancient medical reports, has been recently confirmed by fMRI findings, which showed that seasonality in human cognitive brain functions may influence affective control with annual variations. Thus, seasonality plays a major role in mood disorders, affecting psychopathology, and representing the behavioral

SUBMITTER: Garbazza C 

PROVIDER: S-EPMC6115502 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature