Outdoor Temperature Influences Cold Induced Thermogenesis in Humans.

ABSTRACT: Objective: Energy expenditure (EE) increases in response to cold exposure, which is called cold induced thermogenesis (CIT). Brown adipose tissue (BAT) has been shown to contribute significantly to CIT in human adults. BAT activity and CIT are acutely influenced by ambient temperature. In the present study, we investigated the long-term effect of seasonal temperature variation on human CIT. Materials and Methods: We measured CIT in 56 healthy volunteers by indirect calorimetry. CIT was determined as difference between EE during warm conditions (EE_warm) and after a defined cold stimulus (EE_cold). We recorded skin temperatures at eleven anatomically predefined locations, including the supraclavicular region, which is adjacent to the main human BAT depot. W

SUBMITTER: Senn JR 

PROVIDER: S-EPMC6115528 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature