Morphological Substrates for Atrial Arrhythmogenesis in a Heart With Atrioventricular Septal Defect.

ABSTRACT: Due to advances in corrective surgery, congenital heart disease has an ever growing patient population. Atrial arrhythmias are frequently observed pre- and post-surgical correction. Pharmaceutical antiarrhythmic therapy is not always effective, therefore many symptomatic patients undergo catheter ablation therapy. In patients with atrioventricular septal defects (AVSD), ablation therapy itself has mixed success; arrhythmogenic recurrences are common, and because of the anatomical displacement of the atrioventricular node, 3-degree heart block post-ablation is a real concern. In order to develop optimal and safe ablation strategies, the field of congenital cardiac electrophysiology must combine knowledge from clinical electrophysiology with a thorough understanding of the anatomical substra

SUBMITTER: Stephenson RS 

PROVIDER: S-EPMC6115687 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature