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Genomic Diversity of Listeria monocytogenes Isolated from Clinical and Non-Clinical Samples in Chile.


ABSTRACT: Listeria monocytogenes is the causative agent of listeriosis, which is an uncommon but severe infection associated with high mortality rates in humans especially in high-risk groups. This bacterium survives a variety of stress conditions (e.g., high osmolality, low pH), which allows it to colonize different niches especially niches found in food processing environments. Additionally, a considerable heterogeneity in pathogenic potential has been observed in different strains. In this study, 38 isolates of L. monocytogenes collected in Chile from clinical samples (n = 22) and non-clinical samples (n = 16) were analyzed using whole genome sequencing (WGS) to determine their genomic diversity. A core genome Single Nucleotide Polymorphism (SNP) tree using 55 addition

SUBMITTER: Toledo V 

PROVIDER: S-EPMC6115834 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature