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Metabolomics Biomarkers for Detection of Colorectal Neoplasms: A Systematic Review.


ABSTRACT:

Background

Several approaches have been suggested to be useful in the early detection of colorectal neoplasms. Since metabolites are closely related to the phenotype and are available from different human bio-fluids, metabolomics are candidates for non-invasive early detection of colorectal neoplasms.

Objectives

We aimed to summarize current knowledge on performance characteristics of metabolomics biomarkers that are potentially applicable in a screening setting for the early detection of colorectal neoplasms.

Design

We conducted a systematic literature search in PubMed and Web of Science and searched for biomarkers for the early detection of colorectal neoplasms in easy-to-collect human bio-fluids. Information on study design and performance characteristics for diagn

SUBMITTER: Erben V 

PROVIDER: S-EPMC6116151 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature