Human sperm testicular angiotensin-converting enzyme helps determine human embryo quality.

ABSTRACT: Angiotensin-converting enzyme functions in the male reproductive system, but the extent of its function in reproduction is not fully understood. The primary objective of this work was to investigate the relationship between the testicular isoform of angiotensin-converting enzyme present in human spermatozoa and semen parameters, human embryo quality, and assisted reproduction success. A total of 81 semen samples and 635 embryos from couples undergoing oocyte donation cycles at the IVI Bilbao Clinic were analyzed. Semen parameters, embryos quality, and blastocyst development were examined according to the World Health Organization standards and the Spanish Association of Reproduction Biology Studies criteria. The percentage of testicular angiotensin-converting enzyme-positive spermatozoa an

SUBMITTER: Gianzo M 

PROVIDER: S-EPMC6116683 | biostudies-literature | 2018 Sep-Oct

REPOSITORIES: biostudies-literature