The impact of pharmaceutical innovation on premature cancer mortality in Canada, 2000-2011.

ABSTRACT: The premature cancer mortality rate has been declining in Canada, but there has been considerable variation in the rate of decline across cancer sites. I analyze the effect that pharmaceutical innovation had on premature cancer mortality in Canada during the period 2000-2011, by investigating whether the cancer sites that experienced more pharmaceutical innovation had larger declines in the premature mortality rate, controlling for changes in the incidence rate. Premature mortality before age 75 is significantly inversely related to the cumulative number of drugs registered at least 10 years earlier. Since mean utilization of drugs that have been marketed for less than 10 years is only one-sixth as great as mean utilization of drugs that have been marketed for at least a decade, it is not

SUBMITTER: Lichtenberg FR 

PROVIDER: S-EPMC6116915 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature