Antihyperglycemic drugs use and new-onset atrial fibrillation: A population-based nested case control study.

ABSTRACT: Currently, the potential risk of atrial fibrillation associated with antihyperglycemic drug use has been a topic of considerable interest. However, it remains uncertain whether different classes of antihyperglycemic drug therapy are associated with the risk of atrial fibrillation risk. Here, we investigated the association between different classes of antihyperglycemic drugs and new-onset atrial fibrillation (NAF). A case-matched study was performed based on the National Health Insurance Program in Taiwan. Patients who had NAF were considered the NAF group and were matched in a 1:4 ratio with patients without NAF, who were assigned to the non-NAF group. Patients were matched according to sex, age, diabetes mellitus duration, index date, and Charlson Comorbidity Index score. We used multiva

SUBMITTER: Liou YS 

PROVIDER: S-EPMC6116917 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature