Gene Regulatory Variation in Drosophila melanogaster Renal Tissue.

ABSTRACT: Genetic variation influencing levels of gene expression is abundant in natural populations, and may exert its effects through complex mechanisms that depend on an organism's genetic background and the tissue in which expression is measured. We investigated natural variation in gene expression in the Malpighian tubules of three inbred Drosophila melanogaster strains and their F₁ hybrids. One of the strains was from a population in the species' ancestral range (Zambia), while the other two were from a more recently derived population (Sweden). Although closely related, the two Swedish strains differed greatly in terms of their expression inheritance when hybridized with the Zambian strain, with one Swedish strain showing a large excess of genes with recessive expression inh

SUBMITTER: Glaser-Schmitt A 

PROVIDER: S-EPMC6116969 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature