Economic evaluation of genomic sequencing in the paediatric population: a critical review.

ABSTRACT: Systematic evidence is critical to the formulation of national health policy to provide public funding for the integration of genomic sequencing into routine clinical care. The purpose of this review is to present systematic evidence on the economic evaluation of genomic sequencing conducted for paediatric patients in clinical care, and to identify any gaps in the methodology of economic evaluations. We undertook a critical review of the empirical evidence from economic evaluations of genomic sequencing among paediatric patients searching five electronic databases. Our inclusion criteria were limited to literature published in the English language between 2010 and 2017 in OECD countries. Articles that met our inclusion criteria were assessed using a recognised checklist for a well-designed

SUBMITTER: Alam K 

PROVIDER: S-EPMC6117303 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature