The effects of mid- and long-term endurance exercise on heart angiogenesis and oxidative stress.

ABSTRACT:

Objectives

Long-term, irregular endurance exercise may result in disturbance to the angiogenesis of heart muscles and blood supply. The aim of the present study is to evaluate the effects of mid- and long-term endurance exercise on the process of angiogenesis.

Materials and methods

Eighteen male Wister rats of 220±10 g, were randomly assigned to three groups of 6 rats including: Control, Mid, and Long Group. After the training sessions, the rats were weighed and sacrificed.

Results

In comparison to the Control Group, the both groups, indicated remarkable increase in the weight of heart and significantly higher serum LDH and CK activity (P<0.01). In addition, after the training sessions, weakened antioxidant heart system (TAC, total thiol groups, and GPX activit

SUBMITTER: Ardakanizade M 

PROVIDER: S-EPMC6118080 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature