ADAM33 gene polymorphisms in Southwestern Iranian patients with asthma.

ABSTRACT:

Objectives

Asthma, the most frequent chronic respiratory disease, results from a complex interaction between multiple genes and environmental factors. To date, more than 100 candidate genes and single nucleotide polymorphisms (SNPs) have been reported to be associated with asthma. One of the discovered genes related to asthma is ADAM33. However, the relationship between ADAM33 gene polymorphisms and asthma is controversial. The aim of this study was to investigate the association between four ADAM33 gene SNPs and susceptibility to asthma in patients from southwestern Iran.

Materials and methods

ADAM33 gene polymorphisms at positions T+1 (rs2280091), T1 (rs3918396), S1 (rs2280089), and F+1 (rs511898) were examined in 150 patients with asthma and 14

SUBMITTER: Farjadian S 

PROVIDER: S-EPMC6118084 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature