Cortical fibers orientation mapping using in-vivo whole brain 7 T diffusion MRI.

ABSTRACT: Diffusion MRI of the cortical gray matter is challenging because the micro-environment probed by water molecules is much more complex than within the white matter. High spatial and angular resolutions are therefore necessary to uncover anisotropic diffusion patterns and laminar structures, which provide complementary (e.g. to anatomical and functional MRI) microstructural information about the cortex architectonic. Several ex-vivo and in-vivo MRI studies have recently addressed this question, however predominantly with an emphasis on specific cortical areas. There is currently no whole brain in-vivo data leveraging multi-shell diffusion MRI acquisition at high spatial resolution, and depth dependent analysis, to characterize the complex organization of cortical fibers. Here, we present uni

SUBMITTER: Gulban OF 

PROVIDER: S-EPMC6118131 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature