Distribution of Porphyromonas gingivalis fimA and mfa1 fimbrial genotypes in subgingival plaques.

ABSTRACT:

Background

Strains of periodontal disease-associated bacterium Porphyromonas gingivalis have different pathogenicity, which can be attributed to clonal genetic diversity. P. gingivalis typically expresses two types of fimbriae, FimA and Mfa1, which comprise six (I, Ib, II, III, IV, and V) and two (mfa⁵³ and mfa⁷⁰ ) genotypes, respectively. This study was conducted to investigate the distribution of the two fimbrial genotypes of P. gingivalis in clinical specimens.

Methods

Subgingival plaques were collected from 100 participants during periodontal maintenance therapy and examined for P. gingivalis fimbrial genotypes by direct polymerase chain reaction and/or DNA sequencing. We also analyzed the relationship betwe

SUBMITTER: Nagano K 

PROVIDER: S-EPMC6118206 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature