Prediction of severe acute exacerbation using changes in breathing pattern of COPD patients on home noninvasive ventilation.

ABSTRACT:

Introduction

Acute exacerbation of COPD (AECOPD) is associated with poor outcome. Noninvasive ventilation (NIV) is recommended to treat end-stage COPD. We hypothesized that changing breathing pattern of COPD patients on NIV could identify patients with severe AECOPD prior to admission.

Methods

This is a prospective monocentric study including all patients with COPD treated with long-term home NIV. Patients were divided in two groups: a stable group in which patients were admitted for the usual respiratory review and an exacerbation group in which patients were admitted for inpatient care of severe AECOPD. Data from the ventilator were downloaded and analyzed over the course of the 10 days that preceded the admission.

Results

A total of 62 patients were included: 41 (6

SUBMITTER: Blouet S 

PROVIDER: S-EPMC6118244 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature