Diagnostic value of PD-1 mRNA expression combined with breast ultrasound in breast cancer patients.

ABSTRACT:

Introduction

This study explored the value of measuring programmed death 1 (PD-1) in peripheral blood, combined with breast ultrasound using the Breast Imaging Reporting and Data System (BI-RADS) classification, for differentiation between benign and malignant breast tumors.

Materials and methods

We enrolled 113 patients with breast cancer and 66 patients with benign breast tumors who were admitted to Hangzhou First People's Hospital from September 2014 to August 2017. The mRNA level of PD-1 was detected by quantitative real-time polymerase chain reaction.

Results

The mRNA levels of PD-1 were significantly higher in the peripheral blood of patients with breast cancer than those in patients with benign breast tumors. The diagnostic sensitivity of PD-1 mRNA expression w

SUBMITTER: Fang J 

PROVIDER: S-EPMC6118870 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature