Before and after: craving, mood, and background stress in the hours surrounding drug use and stressful events in patients with opioid-use disorder.

ABSTRACT:

Rationale

Ecological momentary assessment (EMA) of specific events usually focuses more on antecedents and concomitants than on aftermaths.

Objectives

To examine mental state both before and after discrete episodes of stress and drug use.

Methods

For up to 16 weeks, outpatients on opioid-agonist treatment carried smartphones on which they initiated entries for stressful events (SEs) or lapses to drug use (DUs), and thrice daily when randomly prompted (RPs). Participants rated their stress, opioid craving, cocaine craving, and moods. RP entries within 5 h of an event were analyzed and compared to other RPs.

Results

Stress, negative mood, and craving were generally higher before and after DUs and SEs compared to background levels in participants with at least one

SUBMITTER: Preston KL 

PROVIDER: S-EPMC6119104 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature