Characterization of bla_CTX-M sequences of Indian origin and thirteen uropathogenic Escherichia coli isolates resistant to multiple antibiotics.

ABSTRACT:

Objectives

ESBL-producing isolates of the Enterobacteriaceae occur throughout the world. The objectives of this study were to characterize uropathogenic Escherichia coli isolated at a tertiary care hospital in southern India, and shed light on bla_CTX-M sequences of Indian origin.

Results

A cohort of 13 urinary isolates of E. coli (obtained from patients at the Sri Sathya Sai Institute of Higher Medical Sciences, Prasanthigram, Andhra Pradesh, India) were characterized and found to be resistant to multiple antibiotics, including extended-spectrum cephalosporins. All 13 isolates contained bla_CTX-M-15, and many of them transferred this genotype to at least one laboratory strain of E. coli after conjugation. Analyses of bla_CTX-M-15 sequences (n =

SUBMITTER: Siddaramappa S 

PROVIDER: S-EPMC6119312 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature