Longterm Effectiveness of Intraarticular Injections on Patient-reported Symptoms in Knee Osteoarthritis.

ABSTRACT:

Objective

We examined the longterm effectiveness of corticosteroid or hyaluronic acid injections in relieving symptoms among persons with knee osteoarthritis (OA).

Methods

Using Osteoarthritis Initiative data, a new-user design was applied to identify participants initiating corticosteroid or hyaluronic acid injections (n = 412). Knee symptoms (pain, stiffness, function) were measured using The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). We used marginal structural models adjusting for time-varying confounders to estimate the effect on symptoms of newly initiated injection use compared to nonusers over 2 years of followup.

Results

Among 412 participants initiating injections, 77.2% used corticosteroid injections and 22.8% used hyaluronic ac

SUBMITTER: Liu SH 

PROVIDER: S-EPMC6119626 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature