Association of Metabolic Markers with self-reported osteoarthritis among middle-aged BMI-defined non-obese individuals: a cross-sectional study.

ABSTRACT:

Background

Osteoarthritis (OA) is a chronic degenerative joint disease. While it is well-established that obesity affects OA through increased axial loading on the joint cartilage, the indirect effect of obesity through metabolic processes among the body mass index (BMI)-defined non-obese population, i.e., BMI < 30 kg/m², is less known. Our goal was to evaluate the association of metabolic markers including body fat percentage (BF%), waist circumference, maximum weight gain during adulthood and serum creatinine with self-reported OA to establish if such measures offer additional information over BMI among the non-obese population between 40 and 65 years of age.

Methods

Cross-sectional data from two cycles of the Canadian Health Measures Survey (CHMS) in 2007-2009

SUBMITTER: Collins KH 

PROVIDER: S-EPMC6120068 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature