Whole-brain 3D FLAIR at 7T using direct signal control.

ABSTRACT:

Purpose

Image quality obtained for brain imaging at 7T can be hampered by inhomogeneities in the static magnetic field, B₀ , and the RF electromagnetic field, B₁ . In imaging sequences such as fluid-attenuated inversion recovery (FLAIR), which is used to assess neurological disorders, these inhomogeneities cause spatial variations in signal that can reduce clinical efficacy. In this work, we aim to correct for signal inhomogeneities to ensure whole-brain coverage with 3D FLAIR at 7T.

Methods

The direct signal control (DSC) framework was used to optimize channel weightings applied to the 8 transmit channels used in this work on a pulse-by-pulse basis through the echo train in the FLAIR sequences. 3D FLAIR brain images were acquired on 5 different subject

SUBMITTER: Beqiri A 

PROVIDER: S-EPMC6120540 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature