GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens.

ABSTRACT: Current methods struggle to reconstruct and visualize the genomic relationships of large numbers of bacterial genomes. GrapeTree facilitates the analyses of large numbers of allelic profiles by a static "GrapeTree Layout" algorithm that supports interactive visualizations of large trees within a web browser window. GrapeTree also implements a novel minimum spanning tree algorithm (MSTree V2) to reconstruct genetic relationships despite high levels of missing data. GrapeTree is a stand-alone package for investigating phylogenetic trees plus associated metadata and is also integrated into EnteroBase to facilitate cutting edge navigation of genomic relationships among bacterial pathogens.

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC6120633 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature