Effects of exercise on gait and motor imagery in people with Parkinson disease and freezing of gait.

ABSTRACT:

Introduction

Exercise improves gait in Parkinson disease (PD), but whether exercise differentially affects people with PD with (freezers) and without freezing of gait (non-freezers) remains unclear. This study examines exercise's effects on gait performance, neural correlates related to these effects, and potential neural activation differences between freezers and non-freezers during motor imagery (MI) of gait.

Methods

Thirty-seven participants from a larger exercise intervention completed behavioral assessments and functional magnetic resonance imaging (fMRI) scans before and after a 12-week exercise intervention. Gait performance was characterized using gait velocity and stride length, and a region of interest (ROI) fMRI analysis examined task-based blood oxygen-level dep

SUBMITTER: Myers PS 

PROVIDER: S-EPMC6120800 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature