Estimating uterine source current during contractions using magnetomyography measurements.

ABSTRACT: Understanding the uterine source of the electrophysiological activity of contractions during pregnancy is of scientific interest and potential clinical applications. In this work, we propose a method to estimate uterine source currents from magnetomyography (MMG) temporal course measurements on the abdominal surface. In particular, we develop a linear forward model, based on the quasistatic Maxwell's equations and a realistic four-compartment volume conductor, relating the magnetic fields to the source currents on the uterine surface through a lead-field matrix. To compute the lead-field matrix, we use a finite element method that considers the anisotropic property of the myometrium. We estimate the source currents by minimizing a constrained least-squares problem to solve the non-uniquene

SUBMITTER: Zhang M 

PROVIDER: S-EPMC6121809 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature