Strong hybrid male incompatibilities impede the spread of a selfish chromosome between populations of a fly.

ABSTRACT: Meiotically driving sex chromosomes manipulate gametogenesis to increase their transmission at a cost to the rest of the genome. The intragenomic conflicts they produce have major impacts on the ecology and evolution of their host species. However, their ecological dynamics remain poorly understood. Simple population genetic models predict meiotic drivers will rapidly reach fixation in populations and spread across landscapes. In contrast, natural populations commonly show spatial variation in the frequency of drivers, with drive present in clines or mosaics across species ranges. For example, Drosophila subobscura harbors a sex ratio distorting drive chromosome (SRs) at 15-25% frequency in North Africa, present at less than 2% frequency in adjacent southern Spain, and absent

SUBMITTER: Verspoor RL 

PROVIDER: S-EPMC6121854 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature