Intramuscular versus intravenous oxytocin to prevent postpartum haemorrhage at vaginal delivery: randomised controlled trial.

ABSTRACT:

Objective

To determine whether intravenous oxytocin is more effective than intramuscular oxytocin at preventing postpartum haemorrhage at vaginal delivery.

Design

Double blind placebo controlled randomised trial.

Setting

University affiliated maternity unit in the Republic of Ireland.

Participants

1075 women aged 18 years or older, at term with a singleton pregnancy who were aiming for a vaginal delivery with an actively managed third stage of labour.

Interventions

Women were allocated to an intravenous bolus of oxytocin (10 IU in 1 mL given slowly over one minute) and placebo intramuscular injection (1 mL 0.9% saline) or an intramuscular bolus of oxytocin (10 IU in 1 mL) and placebo intravenous injection (1 mL 0.9% saline given slowly over one minute) a

SUBMITTER: Adnan N 

PROVIDER: S-EPMC6122278 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature