Precision medicine in diabetes prevention, classification and management.

ABSTRACT: Diabetes has become a major burden of healthcare expenditure. Diabetes management following a uniform treatment algorithm is often associated with progressive treatment failure and development of diabetic complications. Recent advances in our understanding of the genomic architecture of diabetes and its complications have provided the framework for development of precision medicine to personalize diabetes prevention and management. In the present review, we summarized recent advances in the understanding of the genetic basis of diabetes and its complications. From a clinician's perspective, we attempted to provide a balanced perspective on the utility of genomic medicine in the field of diabetes. Using genetic information to guide management of monogenic forms of diabetes represents the be

SUBMITTER: Xie F 

PROVIDER: S-EPMC6123056 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature