A dedicated anticoagulation clinic does not improve postoperative management of warfarin after total joint arthroplasty.

ABSTRACT:

Background

Periprosthetic joint infections (PJIs) are devastating complications. Excessive anticoagulation with warfarin is an independent risk factor for PJIs. The use of a dedicated anticoagulation clinic to improve warfarin management has not been proven.

Methods

Between 2006 and 2014, we identified 92 patients who were placed on postoperative warfarin, and later developed PJI. These patients were compared to 313 patients who underwent total joint arthroplasty placed on warfarin without developing PJI. Patients were included if they had no history of a venous thromboembolic event, were warfarin naive, and enrolled in the anticoagulation clinic. A univariate analysis compared independent variables, and statistical analysis was performed using Student's t-test and Pearson c

SUBMITTER: Bingham JS 

PROVIDER: S-EPMC6123344 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature