Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers.

ABSTRACT: Wildlife populations are under intense anthropogenic pressures, with the geographic range of many species shrinking, dramatic reductions in population numbers and undisturbed habitats, and biodiversity loss. It is postulated that we are in the midst of a sixth (Anthropocene) mass extinction event, the first to be induced by human activity. Further, threatening vulnerable species is the increased rate of emerging diseases, another consequence of anthropogenic activities. Innovative approaches are required to help maintain healthy populations until the chronic underlying causes of these issues can be addressed. Fibropapillomatosis in sea turtles is one such wildlife disease. Here, we applied precision-medicine-based approaches to profile fibropapillomatosis tumors to better understand their

SUBMITTER: Duffy DJ 

PROVIDER: S-EPMC6123702 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature