The Lifetime Health Burden of Delayed Graft Function in Kidney Transplant Recipients in the United States.

ABSTRACT: Background. Although delayed graft function (DGF) is associated with an increased risk of acute rejection and decreased graft survival, there are no estimates of the long-term or lifetime health burden of DGF. Objectives. To estimate the long-term and lifetime health burden of DGF, defined as the need for at least one dialysis session within the first week after transplantation, for a cohort representative of patients who had their first kidney transplant in 2014. Methods. Data from the United States Renal Data System (USRDS; 2001-2014) were used to estimate a semi-Markov parametric multi-state model with three disease states. Maximum length of follow-up was 13.7 years, and a microsimulation model was used to extrapolate results over a lifetime. The impact of DGF was a

SUBMITTER: Incerti D 

PROVIDER: S-EPMC6124921 | biostudies-literature | 2018 Jan-Jun

REPOSITORIES: biostudies-literature