Efficient and Fair Heart Allocation Policies for Transplantation.

ABSTRACT: Background: The optimal allocation of limited donated hearts to patients on the waiting list is one of the top priorities in heart transplantation management. We developed a simulation model of the US waiting list for heart transplantation to investigate the potential impacts of allocation policies on several outcomes such as pre- and posttransplant mortality. Methods: We used data from the United Network for Organ Sharing (UNOS) and the Scientific Registry of Transplant Recipient (SRTR) to simulate the heart allocation system. The model is validated by comparing the outcomes of the simulation with historical data. We also adapted fairness schemes studied in welfare economics to provide a framework to assess the fairness of allocation policies for transplantation. We consider

SUBMITTER: Hasankhani F 

PROVIDER: S-EPMC6125046 | biostudies-literature | 2017 Jan-Jun

REPOSITORIES: biostudies-literature