Hemolymph protein profiles of subterranean termite Reticulitermes flavipes challenged with methicillin resistant Staphylococcus aureus or Pseudomonas aeruginosa.

ABSTRACT: When the subterranean termite Reticulitermes flavipes is fed heat-killed methicillin resistant Staphylococcus aureus (MRSA) or Pseudomonas aeruginosa, the termite produces proteins with antibacterial activity against the inducer pathogen in its hemolymph. We used a proteomic approach to characterize the alterations in protein profiles caused by the inducer bacterium in the hemolymph of the termite. Nano-liquid chromatography-tandem mass spectrometry analysis identified a total of 221 proteins and approximately 70% of these proteins could be associated with biological processes and molecular functions. Challenges with these human pathogens induced a total of 57 proteins (35 in MRSA-challenged, 16 in P. aeruginosa-challenged, and 6 shared by both treatments) and suppressed 13 proteins by bot

SUBMITTER: Zeng Y 

PROVIDER: S-EPMC6125296 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature