Positive Connectivity Predicts the Dynamic Intrinsic Topology of the Human Brain Network.

ABSTRACT: Functional connectivity MRI (fcMRI) has become instrumental in facilitating research of human brain network organization in terms of coincident interactions between positive and negative synchronizations of large-scale neuronal systems. Although there is a common agreement concerning the interpretation of positive couplings between brain areas, a major debate has been made in disentangling the nature of negative connectivity patterns in terms of its emergence in several methodological approaches and its significance/meaning in specific neuropsychiatric diseases. It is still not clear what information the functional negative correlations or connectivity provides or how they relate to the positive connectivity. Through implementing stepwise functional connectivity (SFC) analysis and studying

SUBMITTER: Qian J 

PROVIDER: S-EPMC6125351 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature