Prevalence and Genetic Analysis of <i>mcr-3</i>-Positive Aeromonas Species from Humans, Retail Meat, and Environmental Water Samples.

ABSTRACT: The mobile colistin resistance gene mcr-3 is globally disseminated in both Enterobacteriaceae and Aeromonas species, with the latter potentially serving as a reservoir for this gene. Here, we investigated the prevalence of mcr-3 in rectal swabs from humans, in food-producing animals and their products, and in the aquatic environment, and we investigated the genetic relationships between the mcr-3-positive isolates. An enriched broth screening method was used to detect mcr-3 in samples, and species identification of isolates from positive samples was carried out by matrix-assisted laser desorption ionization-time of flight mass spectrometry and shotgun sequencing. All mcr-3-positive isolates were subjected to antimicrobial susceptibility test

SUBMITTER: Shen Y 

PROVIDER: S-EPMC6125509 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature