Recruiting young pre-symptomatic children for a clinical trial in type 1 diabetes: Insights from the Fr1da insulin intervention study.

ABSTRACT:

Background

Although detection of children at high risk of developing type 1 diabetes and diagnosis of early stages is possible, up to now there exists no approved therapy to delay or prevent type 1 diabetes. Thus it is vital to develop evidence-based interventions. For this a sufficient number of trial participants is crucial but difficult to obtain especially in asymptomatic children.

Aim

Identifying family characteristics that lead to or impede trial participation and analyze reasons stated by families for non-participation.

Methods

Participants for the Fr1da Insulin Intervention study are recruited from the Fr1da study, a population based screening for early stage type 1 diabetes in Bavaria. Families with eligible children were invited to enroll. We analyzed sex an

SUBMITTER: Kick K 

PROVIDER: S-EPMC6126533 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature