Prevalence of intermediate-stage age-related macular degeneration in patients with acquired immunodeficiency syndrome.

ABSTRACT:

Purpose

To evaluate the prevalence of intermediate-stage age-related macular degeneration (AMD) in patients with acquired immunodeficiency syndrome (AIDS).

Design

Cross-sectional study of patients with AIDS enrolled in the Longitudinal Study of the Ocular Complications of AIDS.

Methods

Intermediate-stage AMD was determined from enrollment retinal photographs by graders at a centralized Reading Center, using the Age-Related Eye Disease Study grading system. Graders were masked as to clinical data.

Results

Of 1825 participants with AIDS and no ocular opportunistic infections, 9.9% had intermediate-stage AMD. Risk factors included age, with an odds ratio (OR) of 1.9 (95% confidence interval [CI] 1.6, 2.3, P < .001) for every decade of age; the prevalence of AMD ra

SUBMITTER: Jabs DA 

PROVIDER: S-EPMC6126535 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature