Walking Speed, Cognitive Function, and Dementia Risk in the English Longitudinal Study of Ageing.

ABSTRACT:

Objectives

To determine the relationships between walking speed, cognitive function, and the interaction between changes in these measures and dementia risk.

Design

Longitudinal observational study.

Setting

English Longitudinal Study of Ageing.

Participants

Individuals aged 60 and older (N=3,932).

Measurements

Walking speed and cognition were assessed at Waves 1 (2002-03) and 2 (2004-05) of the English Longitudinal Study of Ageing. New dementia cases were assessed from Wave 3 (2006-07) to Wave 7 (2014-15). The associations were modelled using Cox proportional hazards regression.

Results

Participants with faster baseline walking speeds were at lower risk of developing dementia (hazard ratio (HR)=0.36, 95% confidence interval (CI)=0.22-0.60). Those

SUBMITTER: Hackett RA 

PROVIDER: S-EPMC6127007 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature