Sensory processing by motoneurons: a numerical model for low-level flight control in flies.

ABSTRACT: Rhythmic locomotor behaviour in animals requires exact timing of muscle activation within the locomotor cycle. In rapidly oscillating motor systems, conventional control strategies may be affected by neural delays, making these strategies inappropriate for precise timing control. In flies, wing control thus requires sensory processing within the peripheral nervous system, circumventing the central brain. The underlying mechanism, with which flies integrate graded depolarization of visual interneurons and spiking proprioceptive feedback for precise muscle activation, is under debate. Based on physiological parameters, we developed a numerical model of spike initiation in flight muscles of a blowfly. The simulated Hodgkin-Huxley neuron reproduces multiple experimental findings and explains o

SUBMITTER: Bartussek J 

PROVIDER: S-EPMC6127168 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature