Association of Kidney Function with Infections by Multidrug-Resistant Organisms: An Electronic Medical Record Analysis.

ABSTRACT: Antibiotic resistance is a major global health threat. High prevalences of colonization and infection with multi-drug resistance organisms (MDROs) have been reported in patients undergoing dialysis. It is unknown if this finding extends to patients with mild and moderate/severe kidney disease. An observational study included all adult incident patients hospitalized with a discharge diagnosis of infection in four hospitals from Guangzhou, China.

Inclusion criteria

Serum creatinine measurement at admission together with microbial culture confirmed infections. Exclusion criterion: Undergoing renal replacement therapy. Four categories of Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) estimated glomerular filtration rate (eGFR) were compared: eGFR ≥ 105, 60-104 (reference),

SUBMITTER: Su G 

PROVIDER: S-EPMC6127257 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature