CO₂ to succinic acid - Estimating the potential of biocatalytic routes.

ABSTRACT: Microbial carbon dioxide assimilation and conversion to chemical platform molecules has the potential to be developed as economic, sustainable processes. The carbon dioxide assimilation can proceed by a variety of natural pathways and recently even synthetic CO₂ fixation routes have been designed. Early assessment of the performance of the different carbon fixation alternatives within biotechnological processes is desirable to evaluate their potential. Here we applied stoichiometric metabolic modeling based on physiological and process data to evaluate different process variants for the conversion of C1 carbon compounds to the industrial relevant platform chemical succinic acid. We computationally analyzed the performance of cyanobacteria, acetogens, methylotrophs, and synthetic

SUBMITTER: Liebal UW 

PROVIDER: S-EPMC6127376 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature