Jugular infusion of arginine has a positive effect on antioxidant mechanisms in lactating dairy cows challenged intravenously with lipopolysaccharide1.

ABSTRACT: The main purpose of this work was to evaluate the effects of jugular l-arginine infusion on antioxidant mechanisms in lactating dairy cows challenged intravenously with lipopolysaccharide (LPS). Eight multiparous Holstein cows (609 ± 32 kg) at midlactation were randomly assigned to 5-d jugular infusions of Control (saline), Arginine (Arg, 18 g/d), LPS (0.2 μg/kg BW per day), and LPS + Arginine (0.2 μg/kg BW per day of LPS and 18 g/d of Arg) in a replicated 4 × 4 Latin square design with 4 infusion periods separated by 10-d. Jugular solutions of saline, Arg, LPS, and LPS + Arg were continuously infused using peristaltic pumps for approximately 6 h/d. Jugular vein serum samples were obtained on the last day of each infusion period before infusion (0 h) and at 3- and 6-h postinfusion. Compare

SUBMITTER: Zhao F 

PROVIDER: S-EPMC6127780 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature