N-of-1 Randomized Intervention Trials in Health Psychology: A Systematic Review and Methodology Critique.

ABSTRACT:

Background

Single-patient, multiple cross-over designs (N-of-1 or single-case randomized clinical trials) with systematic data collection on treatment effects may be useful for increasing the precision of treatments in health psychology.

Purposes

To assess the quality of the methods and statistics, describe interventions and outcomes, and explore the heterogeneity of treatment effect of health psychology N-of-1 trials.

Methods

We conducted a systematic review of N-of-1 trials from electronic database inception through June 1, 2015. Potentially relevant articles were identified by searching the biomedical electronic databases Ovid, MEDLINE, EMBASE, all six databases in the Cochrane Library, CINAHL, and PsycINFO, and conference proceedings, dissertations, ongoing studie

SUBMITTER: Shaffer JA 

PROVIDER: S-EPMC6128372 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature